Besides the usual presenting symptoms of chest pain and shortness of breath, those with malignant mesothelioma may suffer a number of other clinical features, including:
Pleural effusion. This is a collection of fluid in the space between the parietal and visceral pleura. At the time of presentation, >50% of those with malignant mesothelioma have a large pleural effusion
Fever, chills and sweats
Weakness and malaise
Weight loss
Deteriorating performance status
Clotting disorders and pulmonary embolus (a blood clot in the lungs)
Anemia
Those with a pleural effusion are more likely to complain of shortness of breath, while those without one usually have chest pain, weight loss and fever.
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